Immunohistochemical study on keratin proteins of adenosquamous carcinoma of maxillary sinus

A case of adenosquamous carcinoma arising in the maxillary sinus is reported with keratin immunohistochemical evaluations. Adenosquamous carcinoma is a very rare carcinoma of the maxillary sinus. Three cases of adenosquamous carcinoma arising in the maxillary sinus have been reported since 1966. His...

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Bibliographic Details
Published inJournal of Japan Society for Oral Tumors Vol. 8; no. 2; pp. 86 - 93
Main Authors Li, Cuiyang, Ohmura, Hirotoshi, Okamoto, Yoshifumi, Ogawa, Kazuhiro, Mori, Masahiko
Format Journal Article
LanguageJapanese
Published Japanese Society of Oral Oncology 1996
Subjects
adenosquamous cell carcinoma
cytokeratin
immunohistochemistry
maxillary sinus
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Summary:A case of adenosquamous carcinoma arising in the maxillary sinus is reported with keratin immunohistochemical evaluations. Adenosquamous carcinoma is a very rare carcinoma of the maxillary sinus. Three cases of adenosquamous carcinoma arising in the maxillary sinus have been reported since 1966. Histopathologically, tumor tissue composes of tubular carcinoma and squamous cell carcinoma cells. Tissue specimens were evaluated with monoclonal antibody (K4, K7, K8, K10, K13, K17, K18, K19, K20, KL1, and K8.12) using the ABC method. Tubular carcinoma cells were positive with K7, K8, K18, K19, KL1, and K8.12 and squamous cell carcinoma cells were strongly positive with K7, K10, KL1, and K8.12 and weakly positive with K4 and K18. Tubular carcinoma cells formed keratin pairs of K8-18, and squamous cell carcinoma cells formed keratin pairs of K7-17.
ISSN:0915-5988
1884-4995
DOI:10.5843/jsot.8.86