Early introduction of dairy products associated with increased risk of IDDM in Finnish children. The Childhood in Diabetes in Finland Study Group
Early introduction of dairy products associated with increased risk of IDDM in Finnish children. The Childhood in Diabetes in Finland Study Group. S M Virtanen , L Räsänen , K Ylönen , A Aro , D Clayton , B Langholz , J Pitkäniemi , E Savilahti , R Lounamaa and J Tuomilehto Department of Applied Che...
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Published in | Diabetes (New York, N.Y.) Vol. 42; no. 12; pp. 1786 - 1790 |
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Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
American Diabetes Association
01.12.1993
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Subjects | |
Online Access | Get full text |
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Summary: | Early introduction of dairy products associated with increased risk of IDDM in Finnish children. The Childhood in Diabetes
in Finland Study Group.
S M Virtanen ,
L Räsänen ,
K Ylönen ,
A Aro ,
D Clayton ,
B Langholz ,
J Pitkäniemi ,
E Savilahti ,
R Lounamaa and
J Tuomilehto
Department of Applied Chemistry and Microbiology, University of Helsinki, Finland.
Abstract
Associations between infant-feeding patterns and risk of IDDM were investigated in a nationwide Finnish case-control study
of 690 IDDM children < 15 yr of age. Each child was matched by date of birth and sex to a randomly selected population-based
control child. Univariate analysis revealed that the risk of IDDM was increased by approximately 1.5 in children for whom
breast-feeding was terminated at < 2 mo of age, doubled in those who were exclusively breast-fed for < 2 mo, and doubled in
those who were introduced to dairy products at < 2 mo of age. In further multivariate analyses of these factors, it was found
that introduction of dairy products at an early age was the most important risk factor, and the observed univariate effects
of duration of breast-feeding variables were explained by their correlation with this factor. This is the first observational
study to show that early introduction of dairy products is independently associated with an increased risk of IDDM. Adjustment
for mother's education and age, child's birth order, or birth weight did not affect the results. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0012-1797 1939-327X 0012-1797 |
DOI: | 10.2337/diabetes.42.12.1786 |