Hyperhomocysteinemia and in-situ renal artery thrombosis: A diagnostic challenge and a novel treatment strategy

Thrombophilia also known as hypercoagulability or prothrombotic state is an abnormality of blood coagulation that increases the risk of intravascular thrombosis. Hyperhomocysteinemia is a prothrombotic condition characterized by an abnormally high level of homocysteine in the blood, conventionally d...

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Bibliographic Details
Published inIndian journal of medical specialities Vol. 6; no. 3; pp. 111 - 115
Main Authors Sahu, Rakesh, Murthy, Ashwini
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.07.2015
Subjects
Renal infarction
Tenecteplase
Thrombolytic therapy
Thrombophilia
Thrombophilia
Tenecteplase
Renal infarction
Thrombolytic therapy
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Summary:Thrombophilia also known as hypercoagulability or prothrombotic state is an abnormality of blood coagulation that increases the risk of intravascular thrombosis. Hyperhomocysteinemia is a prothrombotic condition characterized by an abnormally high level of homocysteine in the blood, conventionally described as above 15μmol/L. Both venous as well as arterial thromboembolisms are associated with it. We report the case of a young patient with hyperhomocysteinemia, who presented with recurrent arterial thrombosis, particularly renal artery thrombosis and its successful treatment with catheter directed intra-arterial thrombolysis using Tenecteplase.
ISSN:0976-2884
0976-2892
DOI:10.1016/j.injms.2015.06.002