Applying Mössbauer spectroscopy to studies of red blood cells in donated blood

Samples of packed red blood cells (PRBC) from standard containers for storing donated blood (35 days as per GOST) are studied. Samples for Mössbauer spectroscopy studies are taken from each container every few days over the period of storage. Analysis of the Mössbauer spectra yield data on variation...

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Published inBulletin of the Russian Academy of Sciences. Physics Vol. 77; no. 6; pp. 726 - 729
Main Authors Khvastunov, S. M., Novakova, A. A., Kiseleva, T. Yu
Format Journal Article
LanguageEnglish
Published Boston Springer US 01.06.2013
Springer Nature B.V
Subjects
Containers
Erythrocytes
Hadrons
Heavy Ions
Hemoglobin
Nuclear Physics
Physics
Physics and Astronomy
Proceedings of the 12th International Conference “Mössbauer Spectroscopy and its Applications”
Spectroscopic analysis
Spectrum analysis
Storage
Storage Phase
Storage Term
Kinetic Curf
Blood Preparation
Tezisy Dokladov
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Summary:Samples of packed red blood cells (PRBC) from standard containers for storing donated blood (35 days as per GOST) are studied. Samples for Mössbauer spectroscopy studies are taken from each container every few days over the period of storage. Analysis of the Mössbauer spectra yield data on variations in the content of different forms of hemoglobin and its derivatives in the samples studied over the storage period. Analysis of the plotted kinetic curves representing changes in the content of these forms provide estimates of the functional states of PRBC from each donor in different storage phases. Revealed distinctions in the kinetics of changes taking place in PRBC from different donors provide data on the effect of individual features of particular donors on the PRBC degradation process.
ISSN:1062-8738
1934-9432
DOI:10.3103/S1062873813060178