Parameters of cardiac muscle repolarization on the electrocardiogram when changing anatomical and electric position of the heart

• Published in: Biophysics (Oxford) Vol. 59; no. 5; pp. 820 - 828
• Main Authors: Chaikovsky, I. A., Baum, O. V., Popov, L. A., Voloshin, V. I., Budnyk, N. N., Frolov, Yu. A., Kovalenko, A. S.
• Format: Journal Article
• Language: English
• Published: Moscow Pleiades Publishing 01.09.2014; Springer Nature B.V
• Subjects: Biological and Medical Physics; Biophysics; Complex Systems Biophysics; Electrocardiography; Heart; Ischemia; Medical diagnosis; Musculoskeletal system; Physics; Physics and Astronomy; repolarization; transmembrane action potential; electrocardiogram; ST-T interval; myocardial ischemia; mathematical and computer modeling
• ISSN: 0006-3509; 1555-6654
• DOI: 10.1134/S0006350914050066

While discussing the diagnostic value of the single channel electrocardiogram a set of theoretical considerations emerges inevitably, one of the most important among them is the question about dependence of the electrocardiogram parameters from the direction of electrical axis of heart. In other words, changes in what of electrocardiogram parameters are in fact liable to reflect pathological processes in myocardium, and what ones are determined by extracardiac factors, primarily by anatomic characteristics of patients. It is arguable that while analyzing electrocardiogram it is necessary to orient to such physiologically based informative indexes as ST segment displacement. Also, symmetry of the T wave shape is an important parameter which is independent of patients anatomic features. The results obtained are of interest for theoretical and applied aspects of the biophysics of the cardiac electric field.