Müller Cells: Genii Loci

Müller cells are the major type of glial cells in the retina and are actively involved in ensuring its vital functions. They are responsible for maintaining homeostasis and the synaptic activity of neurons by transporting substances to all types of cells within the retina and leading them beyond it....

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Bibliographic Details
Published inHuman physiology Vol. 46; no. 6; pp. 696 - 702
Main Authors Tikhonovich, M. V., Gavrilova, S. A., Ioshin, I. E.
Format Journal Article
LanguageEnglish
Published Moscow Pleiades Publishing 01.11.2020
Springer Nature B.V
Subjects
Biomedical and Life Sciences
Biomedicine
Cytology
Glial cells
Homeostasis
Human Physiology
Life Sciences
Photoreceptors
Retina
Reviews
Müller cells
light guiding
retina
regeneration
glia
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Summary:Müller cells are the major type of glial cells in the retina and are actively involved in ensuring its vital functions. They are responsible for maintaining homeostasis and the synaptic activity of neurons by transporting substances to all types of cells within the retina and leading them beyond it. Müller cells guide light to photoreceptors, dividing it according to the wavelength and amplifying the incoming light signal, they protect neurons from damage and are able to regenerate into photoreceptors and other retinal cells under pathological conditions. This review summarizes the knowledge about the morphology and functions of Müller cells which has been accumulated over the years of their study.
ISSN:0362-1197
1608-3164
DOI:10.1134/S0362119720050126