A PATIENT WITH SMALL CELL CARCINOMA OF THE STOMACH WHO SURVIVED FOR 2 YEARS AND 7 MONTHS AFTER RESECTION OF HEPATIC METASTASIS

• Published in: Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) Vol. 60; no. 10; pp. 2652 - 2655
• Main Authors: KAWAMOTO, Kazuyuki, OGASAHARA, Keizo, OKADA, Noriyuki, KOUNO, Yukihiro, TAKASAN, Hidenari
• Format: Journal Article
• Language: English
• Published: Japan Surgical Association 25.10.1999
• ISSN: 1345-2843; 1882-5133
• DOI: 10.3919/jjsa.60.2652

A patient with small cell carcinoma of the stomach who survived for 2 years and 7 months after resection of hepatic metastasis is reported. A 58-year-old man complaining of abdominal pain and diarrhea was referred to the hospital because a gastric radiography revealed a niche at the greater curvature of the middle body of the stomach at another hospital. After admission to the hospital, endoscopic examination of the stomach revealed a Borrmann type 2 tumor, and biopsy demonstrated poorly differentiated adenocarcinoma. A distal gastrectomy with D2 dissection was performed (T3, N1, H0, P0). An ulcerative tumor, 2×2cm in size, was composed of small atypical cells with chromatin-riched nucleus. Immunohistochemically, these small cells were stained positive for NSE and chromogranin A. Therefore, this tumor was diagnosed as small cell carcinoma of the stomach. Six months later, liver metastasis was found by CT scan examination, and a partial he-patectomy was performed. The CDDP and 5 FU therapy was regularly conducted. This patient died of multiple lung metastases and bone metastases 2 years and 7 months after the recection of the liver metastasis.