Review article: sodium starch glycolate as a super disintegrant

Sodium starch glycolate (SSG) is most widely used excipient in the field of pharmaceutical sciences. SSG is extensively used as a superdisintegrant in different drug formulations. This review article aims to discuss chemistry, synthesis, level used as superdisintegrant, different types of SSG’s and...

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Bibliographic Details
Published inJournal of Contemporary Pharmacy Vol. 5; no. 1
Main Author Aneela Manzoor
Format Journal Article
LanguageEnglish
Published AMMANIF 31.07.2021
Subjects
Compaction
Fast dissolution
SSG
Substitution
Superdisintegrant
Swelling
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Summary:Sodium starch glycolate (SSG) is most widely used excipient in the field of pharmaceutical sciences. SSG is extensively used as a superdisintegrant in different drug formulations. This review article aims to discuss chemistry, synthesis, level used as superdisintegrant, different types of SSG’s and various physicochemical properties. SSG available as different brands i.e Primojel, Explotab and Vivastar with different properties. Excipient, generally considered as an inert component, are of great importance in drug product development. Interchange between different suppliers can lead to final products with different quality attributes
ISSN:2521-0521
DOI:10.56770/jcp2021515