Association of body type and hemoglobin A1c levels and risk of lifestyle-related diseases in young women

• Published in: Journal for the Integrated Study of Dietary Habits Vol. 27; no. 4; pp. 243 - 248
• Main Authors: Miyauchi, Maki, Suzuki, Yoshio, Sakuraba, Keishoku, Fukao, Kosuke
• Format: Journal Article
• Language: English; Japanese
• Published: THE JAPAN ASSOCIATION FOR THE INTEGRATED STUDY OF DIETARY HABITS 2017
• ISSN: 1346-9770; 1881-2368
• DOI: 10.2740/jisdh.27.4_243

[Background]　Hemoglobin A1c (HbA1c) concentration was high (≥ 5.6％) in 34％ of women aged 20-39 years in Choshi City, Chiba prefecture who underwent medical checks during June and July 2014. The ratio was higher than that of women aged 40-44 years in all of Chiba prefecture (19％). Among the women with high HbA1c concentrations in Choshi City, 64％ had a normal body mass index (BMI) of 18.5-25.0.[Objective]　To determine the risk of lifestyle-related diseases among young women with high HbA1c levels and a normal BMI in Choshi City.[Methods]　Women with a BMI within the normal range who underwent medical checks during 2014 were assigned to groups with high (≥ 5.6％; n ＝ 89) and normal (＜ 5.6％; n ＝ 188) HbA1c concentrations. The outcomes of their medical checks were compared. We also assessed eating habits of women with high HbA1c using a brief-type self-administered diet history questionnaire (BDHQ; n ＝ 24), along with body composition and quantitative calcaneal ultrasound sonometry (n ＝ 14).[Results]　The mean serum LDL-cholesterol concentration was higher (p ＝ 0.034), whereas hemoglobin concentration and diastolic blood pressure were lower (p ＜ 0.001 and p ＝ 0.007, respectively) in the group with high, compared with normal HbA1c. More items were outside normal ranges in the group with high HbA1c (p ＜ 0.001). The body fat percentage was ≥ 30％ in 46％ of the participants, which was classified as normal-weight obesity or hidden obesity.[Conclusions]　In this study, the young women with a normal range and high HbA1c were suggested to have higher risk of lifestyle-related diseases. Almost half of them were classified as having hidden obesity.