Antimicrobial resistance in Klebsiella pneumoniae : an overview of common mechanisms and a current Canadian perspective

is a ubiquitous opportunistic pathogen of the family Enterobacteriaceae. is a member of the ESKAPEE pathogens ( spp., and ), a group of bacteria that cause nosocomial infections and are able to resist killing by commonly relied upon antimicrobial agents. The acquisition of antimicrobial resistance (...

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Bibliographic Details
Published inCanadian journal of microbiology
Main Authors Braun, Hannah G, Perera, Sumudu R, Tremblay, Yannick Dn, Thomassin, Jenny-Lee
Format Journal Article
LanguageEnglish
Published Canada 30.08.2024
Subjects
antibiotic resistance
antimicrobial resistance
Klebsiella pneumoniae
biofilm
One Health
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Summary:is a ubiquitous opportunistic pathogen of the family Enterobacteriaceae. is a member of the ESKAPEE pathogens ( spp., and ), a group of bacteria that cause nosocomial infections and are able to resist killing by commonly relied upon antimicrobial agents. The acquisition of antimicrobial resistance (AMR) genes is increasing among community and clinical isolates of making a rising threat to human health. In addition to the increase in AMR, is also thought to disseminate AMR genes to other bacterial species. In this review, the known mechanisms of AMR will be described and the current state of AMR within Canada will be discussed, including the impact of the coronavirus disease-2019 pandemic, current perspectives, and outlook for the future.
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ISSN:0008-4166
1480-3275
1480-3275
DOI:10.1139/cjm-2024-0032