Asthmatics Have Decreased Sputum Macrophage Surface Phenotype Expression Compared to Healthy Subjects Following In Vitro Exposure to Organic Dust

Conclusions Organic dust exposure down-regulates cell surface phenotype expression associated with antigen presentation and host defense on airway macrophages from asthmatics.

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Bibliographic Details
Published inJournal of allergy and clinical immunology Vol. 121; no. 2; p. S66
Main Authors Alexis, N.E, Lay, J.C, Peden, D.B, Poole, J.A
Format Journal Article
LanguageEnglish
Published St. Louis Mosby, Inc 01.02.2008
Elsevier Limited
Subjects
Allergy and Immunology
Asthma
Dust
Genotype & phenotype
Medical research
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Summary:Conclusions Organic dust exposure down-regulates cell surface phenotype expression associated with antigen presentation and host defense on airway macrophages from asthmatics.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2007.12.265