Effect of cataract in Fourier‐Domain OCT measurements using two Optical Coherence Tomography

• Published in: Acta ophthalmologica (Oxford, England) Vol. 89; no. s248
• Main Authors: GARCIA MARTIN, E, SANCHO MORO, E, HERRERO LATORRE, R, GIL‐ARRIBAS, L, IDOIPE, M, FERNANDEZ‐PEREZ, S, PINILLA, I, PRIETO CALVO, E, DE LA MATA, G
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.09.2011; Wiley Subscription Services, Inc
• Subjects: Cataracts; Eye surgery; Retina; Surgery; Tomography
• ISSN: 1755-375X; 1755-3768
• DOI: 10.1111/j.1755-3768.2011.237.x

Purpose To evaluate the effect of cataract in retinal nerve fiber layer (RNFL) thickness measurements using Fourier‐domain (FD) Optical Coherence Tomography (OCT). To test the intra‐session reproducibility of RNFL thickness measurements and the quality of images in patients before and after the cataract surgery using Cirrus and Spectralis OCT. Methods Thirty eyes of 30 subjects (15 men and 15 women; aged from 67 to 86 years) underwent three 360° circular scans centred on the optic disc by the same experienced examiner using the Cirrus and Spectralis OCT instruments one month before and one month after cataract surgery. Differences between the two visits were analyzed. Repeatability was studied by intra‐class correlation coefficients and coefficients of variation (COV) for both visits and OCTs. The quality of images was also compared between the visits. Results RNFL differences were detected between both visits for temporal and nasal quadrant (p<0.05). RNFL average thickness was 95.4 µm in pre‐surgery visit and 96.1 µm in post‐surgery visit with Cirrus OCT; and 99.0 µm vs 102.4 µm using Spectralis OCT. Reproducibility was good in both visits, but it achieved higher values in post‐surgery evaluation (mean COV of 5.61% in first visit vs 4.44% in second visit using Cirrus, and 5.76% vs 4.12% using Spectralis). Intra‐class correlation coefficients were higher than 0.818. The quality of images was better in post‐surgery evaluations. Conclusion Cataract affects RNFL thickness measurements, reproducibility and the quality of images obtained by Cirrus and Spectralis OCT.