Unbiased RNA Sequencing of Acute Respiratory Syncytial Virus Infection Reveals Gene Expression Signatures that Provide Insight into Pathogenesis

Conclusions Host gene expression profiles obtained during acute RSV infections provide unprecedented insight into the mechanisms that cause pathogenesis and long-term impacts, such as the development of asthma, which may ultimately guide clinical treatment and management decisions for children with...

Full description

Saved in:
Bibliographic Details
Published inJournal of allergy and clinical immunology Vol. 139; no. 2; p. AB270
Main Authors Dinwiddie, Darrell L., PhD, Kennedy, Joshua, MD, Dehority, Walter N., MD, Schwalm, Kurt, BS, Langley, Raymond J., PhD, Young, Stephen A., PhD
Format Journal Article
LanguageEnglish
Published St. Louis Elsevier Inc 01.02.2017
Elsevier Limited
Subjects
Allergy and Immunology
Asthma
Gene expression
Infections
Pathogenesis
Respiratory syncytial virus
Viruses
Online AccessGet full text

Cover

More Information
Summary:Conclusions Host gene expression profiles obtained during acute RSV infections provide unprecedented insight into the mechanisms that cause pathogenesis and long-term impacts, such as the development of asthma, which may ultimately guide clinical treatment and management decisions for children with severe infections.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2016.12.871