Evaluation of Organ-Specific Autoimmunity and Humoral Immunodeficiency in Patients with Juvenile Dermatomyositis (JDM)

Methods Twenty-nine children with JDM followed at the Pediatric Rheumatology Unit of a tertiary hospital were investigated for the presence of the following serum antibodies: antinuclear (ANA), anti-double-stranded DNA, anti-Sm, anti-ribonucleoprotein, anti-SSA/SSB, anti-Jo-1, anti-Scl-70, anticardi...

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Published inJournal of allergy and clinical immunology Vol. 121; no. 2; p. S227
Main Authors Aikawa, N.E, Liphaus, B.L, Silva, C.A.A, Sampaio, M.C, Sallum, A.M.E
Format Journal Article
LanguageEnglish
Published St. Louis Mosby, Inc 01.02.2008
Elsevier Limited
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Summary:Methods Twenty-nine children with JDM followed at the Pediatric Rheumatology Unit of a tertiary hospital were investigated for the presence of the following serum antibodies: antinuclear (ANA), anti-double-stranded DNA, anti-Sm, anti-ribonucleoprotein, anti-SSA/SSB, anti-Jo-1, anti-Scl-70, anticardiolipin (aCL), lupus anticoagulant, rheumatoid factor, perinuclear antineutrophil cytoplasmic and cytoplasmic antineutrophil cytoplasmic (c-ANCA), anti-smooth muscle (SMA), anti-liver-kidney microsomal type 1, anti-mitochondrial, anti-endomysium (EMA), anti-gastric parietal cells, anti-insulin (IAA), anti-glutamic acid decarboxylase (anti-GAD), anti-thyroid peroxidase, anti-thyroglobulin (TGA) and anti-thyrotropin receptor (TRab).
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2007.12.896