Evaluation of Organ-Specific Autoimmunity and Humoral Immunodeficiency in Patients with Juvenile Dermatomyositis (JDM)

Methods Twenty-nine children with JDM followed at the Pediatric Rheumatology Unit of a tertiary hospital were investigated for the presence of the following serum antibodies: antinuclear (ANA), anti-double-stranded DNA, anti-Sm, anti-ribonucleoprotein, anti-SSA/SSB, anti-Jo-1, anti-Scl-70, anticardi...

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Published inJournal of allergy and clinical immunology Vol. 121; no. 2; p. S227
Main Authors Aikawa, N.E, Liphaus, B.L, Silva, C.A.A, Sampaio, M.C, Sallum, A.M.E
Format Journal Article
LanguageEnglish
Published St. Louis Mosby, Inc 01.02.2008
Elsevier Limited
Subjects
Allergy and Immunology
Autoimmune diseases
Patients
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Summary:Methods Twenty-nine children with JDM followed at the Pediatric Rheumatology Unit of a tertiary hospital were investigated for the presence of the following serum antibodies: antinuclear (ANA), anti-double-stranded DNA, anti-Sm, anti-ribonucleoprotein, anti-SSA/SSB, anti-Jo-1, anti-Scl-70, anticardiolipin (aCL), lupus anticoagulant, rheumatoid factor, perinuclear antineutrophil cytoplasmic and cytoplasmic antineutrophil cytoplasmic (c-ANCA), anti-smooth muscle (SMA), anti-liver-kidney microsomal type 1, anti-mitochondrial, anti-endomysium (EMA), anti-gastric parietal cells, anti-insulin (IAA), anti-glutamic acid decarboxylase (anti-GAD), anti-thyroid peroxidase, anti-thyroglobulin (TGA) and anti-thyrotropin receptor (TRab).
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2007.12.896