Safety of 20% Serum Eye Drops In-House Prescription
We investigated the contamination risk of 20% serum eye drops after 1 week of their use. Fifteen bottles containing 20% serum eye drops were prepared under aseptic conditions using serum eye drops obtained from three subjects without eye diseases and were stored at 5℃. The bottles were placed under...
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Published in | Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences) Vol. 43; no. 7; pp. 401 - 403 |
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Main Authors | , , , |
Format | Journal Article |
Language | Japanese English |
Published |
Japanese Society of Pharmaceutical Health Care and Sciences
10.07.2017
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Subjects | |
Online Access | Get full text |
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Summary: | We investigated the contamination risk of 20% serum eye drops after 1 week of their use. Fifteen bottles containing 20% serum eye drops were prepared under aseptic conditions using serum eye drops obtained from three subjects without eye diseases and were stored at 5℃. The bottles were placed under running water in a washbasin eight times daily for 7 days. All bottles were placed under running water on the first day, 12 on the second day, nine on the third day, six on the fourth day, and three from the fifth to the seventh days. Residual sera from three bottles placed under running water on the first to the fourth day and on the seventh day were cultured for 14 days using thioglycollate broth. No bacterial growth was detected in the broth. From the results, we found that the 20% serum eye drops remained aseptic after 1 week of use. |
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ISSN: | 1346-342X 1882-1499 |
DOI: | 10.5649/jjphcs.43.401 |