A transposon-based tumor resection model of pancreatic ductal adenocarcinoma (PDAC) with extrahepatic distant metastases

[...]the recurrence patterns of our resection model reflects the clinical situation in humans, it holds promise for preclinical evaluation of novel multimodal and adjuvant therapies in genetically defined pancreatic cancers to prevent recurrence and outgrowth of metastases after R0-resection.

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Bibliographic Details
Published inPancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] Vol. 13; no. 3; p. S25
Main Authors Gürlevik, Engin, Fleischmann-Mundt, Bettina, Calvisi, Diego, Armbrecht, Nina, Ribback, Silvia, Manns, Michael, Dombrowski, Frank, Evert, Matthias, Zender, Lars, Kühnel, Florian, Kubicka, Stefan
Format Journal Article
LanguageEnglish
Published Philadelphia Elsevier B.V 01.05.2013
Elsevier Limited
Subjects
Endocrinology & Metabolism
Gastroenterology and Hepatology
Medical prognosis
Metastasis
Plasmids
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Summary:[...]the recurrence patterns of our resection model reflects the clinical situation in humans, it holds promise for preclinical evaluation of novel multimodal and adjuvant therapies in genetically defined pancreatic cancers to prevent recurrence and outgrowth of metastases after R0-resection.
ISSN:1424-3903
1424-3911
DOI:10.1016/j.pan.2013.04.077