Modifying oncolytic viral therapy for pancreatic cancer

Targeting avb6 -integrin expressing pancreatic cancer cells with oncolytic adenoviral mutants expressing a FMDV peptide (Ad5-FMDV): Diagnosis of pancreatic ductal adenocarcinomas (PDAC) often occurs too late for effective treatment due to non-specific presentation of symptoms.

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Bibliographic Details
Published inPancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] Vol. 16; no. 3; p. S4
Main Authors Man, Y.K. Stella, Pantelidou, Constantia, Blázquez-Moreno, Alfonso, Coughlan, Lynda, Marshall, John, Kocher, Hemant, Halldén, Gunnel
Format Journal Article
LanguageEnglish
Published Philadelphia Elsevier B.V 01.06.2016
Elsevier Limited
Subjects
Endocrinology & Metabolism
Gastroenterology and Hepatology
Pancreatic cancer
Peptides
Viruses
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Summary:Targeting avb6 -integrin expressing pancreatic cancer cells with oncolytic adenoviral mutants expressing a FMDV peptide (Ad5-FMDV): Diagnosis of pancreatic ductal adenocarcinomas (PDAC) often occurs too late for effective treatment due to non-specific presentation of symptoms.
ISSN:1424-3903
1424-3911
DOI:10.1016/j.pan.2016.04.017