Dexmedetomidine for Neurosurgical Procedures

While earlier clinical investigations focused on characterizing the physiologic effects of dexmedetomidine and its role as a sedative drug in critically-ill patients, newer studies suggest that the alpha 2 adrenergic receptor agonist may have a role as an adjunct in intraoperative neuroanesthesia. D...

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Bibliographic Details
Published inCurrent anesthesiology reports (Philadelphia) Vol. 3; no. 3; pp. 205 - 209
Main Authors Schwarz, Adam, Nossaman, Bobby, Carollo, Dominic, Ramadhyani, Usha
Format Journal Article
LanguageEnglish
Published Boston Springer US 01.09.2013
Subjects
Anesthesiology
Critical Care Medicine
Intensive
Internal Medicine
Medicine
Medicine & Public Health
Neuroanesthesia (JJ Pasternak
Section Editor
Neuroprotection
Awake craniotomy
Cerebral blood flow
Cardiovascular effects
Dexmedetomidine
Neurophysiologic monitoring
Alpha receptor agonist
Pediatric patients
Sedation and analgesia
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Summary:While earlier clinical investigations focused on characterizing the physiologic effects of dexmedetomidine and its role as a sedative drug in critically-ill patients, newer studies suggest that the alpha 2 adrenergic receptor agonist may have a role as an adjunct in intraoperative neuroanesthesia. Dexmedetomidine has been shown to have multiple favorable clinical effects such as lack of respiratory depression, neuroprotection, hemodynamic stability, and no apparent interference with intraoperative neurophysiologic monitoring. This suggests that dexmedetomidine can be useful in the management of neurosurgical patients.
ISSN:2167-6275
2167-6275
DOI:10.1007/s40140-013-0021-x