Review Article: Involvement of the Gut Microbiome and Probiotic Interventions in Pediatric Acute Lymphoblastic Leukemia

• Published in: Critical reviews in oncogenesis Vol. 30; no. 2; p. 13
• Main Author: Navasardyan, Inesa
• Format: Journal Article
• Language: English
• Published: United States 2025
• Subjects: Child; Child, Preschool; Gastrointestinal Microbiome - drug effects; Gastrointestinal Microbiome - immunology; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma - microbiology; Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy; Probiotics - therapeutic use

Acute lymphoblastic leukemia (ALL) is a common pediatric cancer marked by uncontrolled proliferation of lymphoblasts, primarily affecting children aged two to five years. While treatment success rates have reached 90% in children, challenges such as therapy toxicity and relapse persist. The gut micr...