Association between objective measures of oral health and salivary gland irradiation with patient-reported outcomes following head and neck radiation therapy

• Published in: Head & neck
• Main Authors: Singh, Annu, Long, Sallie M, Tin, Amy L, Vickers, Andrew J, Yom, SaeHee K, Lee, Nancy Y, Huryn, Joseph M, Cracchiolo, Jennifer R, Estilo, Cherry L
• Format: Journal Article
• Language: English
• Published: United States 20.07.2024
• Subjects: oral health‐related quality of life; objective measures; patient‐reported outcomes; head and neck radiation therapy; salivary gland irradiation
• ISSN: 1043-3074; 1097-0347; 1097-0347
• DOI: 10.1002/hed.27884

To determine whether objective measures of oral health and salivary gland irradiation correlates with subjective measures of eating, drinking, and salivation in patients following head and neck radiation therapy (HNRT). This cross-sectional study included 112 patients following HNRT with a completed patient-reported outcome (PRO) scale. Objective measures at post-HNRT visit included decayed-missing-filled teeth (DMFT) scores, periodontal disease condition, oral hygiene status, dental prosthesis use, and prescribed radiation dose to salivary glands. Data were collected and statistical analysis was performed. There was no significant association between PRO scales and dental prosthesis use, periodontal disease, and oral hygiene. Although some significant findings were seen with DMFT and prescribed radiation dose to salivary glands, this explained only very small amounts of the variation in eating, drinking, and salivation measures in these patients. PRO measures should be integrated in the routine care of patients with head and neck cancer.