3D Bioprinting of Engineered Tissue Flaps with Hierarchical Vessel Networks (VesselNet) for Direct Host‐To‐Implant Perfusion (Adv. Mater. 42/2021)

3D Bioprinting Millimetric tubular scaffolds and 3D bioprinted vascularized collagen hydrogels are combined by Shulamit Levenberg and co‐workers in article number 2102661 to create engineered hierarchically vascularized tissues (engineered flap) consisting of rich microvascular networks in communica...

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Bibliographic Details
Published inAdvanced materials (Weinheim) Vol. 33; no. 42
Main Authors Szklanny, Ariel A., Machour, Majd, Redenski, Idan, Chochola, Václav, Goldfracht, Idit, Kaplan, Ben, Epshtein, Mark, Simaan Yameen, Haneen, Merdler, Uri, Feinberg, Adam, Seliktar, Dror, Korin, Netanel, Jaroš, Josef, Levenberg, Shulamit
Format Journal Article
LanguageEnglish
Published 21.10.2021
Subjects
3D bioprinting
ECM bioink
engineered flap
personalized medicine
tissue engineering
vascularization
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Summary:3D Bioprinting Millimetric tubular scaffolds and 3D bioprinted vascularized collagen hydrogels are combined by Shulamit Levenberg and co‐workers in article number 2102661 to create engineered hierarchically vascularized tissues (engineered flap) consisting of rich microvascular networks in communication with an engineered endothelium. The in vitro cultured flaps are directly anastomosed to the host vasculature, successfully perfusing the implanted tissue. This work represents a step forward to achieving large fully engineered human tissues.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.202170335