Budd-Chiari Syndrome Due to Protein C Deficiency: A Rare Disorder to cause Chronic Liver Disease

• Published in: Euroasian journal of hepato-gastroenterology Vol. 6; no. 2; pp. 194 - 197
• Main Authors: Begum, Rukshana, Mahtab, Mamun Al, Mamun, Ayub Al, Moben, Ahmed Lutful, Hossain, Sharker Mohammad Shahadat, Das, Dulal Chandra, Malakar, Debraj, Or Rashid, Harun, Roy, Partho Protim, Rahman, Salimur
• Format: Journal Article
• Language: English
• Published: India Jaypee Brothers Medical Publishers 01.07.2016
• Subjects: Case Report; Protein C deficiency; Rare disorder; Budd–Chiari Syndrome
• ISSN: 2231-5047; 2231-5128
• DOI: 10.5005/jp-journals-10018-1199

The Budd-Chiari syndrome (BCS) is a rare disorder due to chronic liver disease (CLD), which is caused by the obstruction of hepatic venous outflow that can be located at any place from the small hepatic venules up to the entrance of the inferior vena cava (IVC) into the right atrium. Among the causes of BCS, the rarer one is coagulation factor deficiencies. Here, we report a case of BCS associated with deficiency of protein C resulting in thrombus in IVC. The patient was a 50-year-old male, who had been suffering from recurrent abdominal and leg swelling for a long period of 7 years. He was evaluated thoroughly, and other causes of liver cirrhosis were excluded. Begum R, Al Mahtab M, Al Mamun A, Moben AL, Hossain SMS, Das DC, Malakar D, Rashid HO, Roy PP, Rahman S. Budd-Chiari Syndrome Due to Protein C Deficiency: A Rare Disorder to cause Chronic Liver Disease. Euroasian J Hepato-Gastroenterol 2016;6(2):194-197.