Drug Compatibility in Treatment of Chronic Infectious Diseases

The article considers the features of pharmacotherapy of patients with chronic infectious diseases and co-morbidities in conditions of polypharmacy, the principles of drug metabolism, variants of adverse effects and drug-drug interactions, the possibilities of effective drug combinations. The purpos...

Full description

Saved in:
Bibliographic Details
Published inArkhivʺ vnutrenneĭ medit͡s︡iny Vol. 11; no. 5; pp. 344 - 358
Main Authors Bazrova, E. S., Kaminskiy, G. D., Ilchenko, L. Yu, Маtin, A., Nikitin, I. G.
Format Journal Article
LanguageEnglish
Russian
Published SINAPS LLC 28.09.2021
Subjects
anti-retroviral therapy
chronic infectious diseases
comorbidity
drug compatibility
drug-drug interactions
hiv infection
pharmacotherapy
polypharmacy
tuberculosis
Online AccessGet full text

Cover

More Information
Summary:The article considers the features of pharmacotherapy of patients with chronic infectious diseases and co-morbidities in conditions of polypharmacy, the principles of drug metabolism, variants of adverse effects and drug-drug interactions, the possibilities of effective drug combinations. The purpose is to substantiate the possibility and emphasize the relevance of the additional search of the creation of the most optimal combinations of drugs for long-term and massive pharmacotherapy, that could be due to a beneficial drug-drug interaction, optimization of the regimen, route of drug administration and multitarget of the therapeutic effect, reduce the pharmacological load while maintaining the effectiveness of the treatment, increase patient adherence to drug therapy.
ISSN:2226-6704
2411-6564
DOI:10.20514/2226-6704-2021-11-5-344-358