Notizen: Trennung und biologische Wirksamkeit der Enantiomeren eines chiralen Thiadiazolylsulfoxides/Separation and Biological Activity of the Enantiomers of a Chiral Thiadiazolyl Sulfoxide

The enantiomers of the fungicidal and bactericidal (3-chloro-1,2,4-thiadiazol-5-yl)-(3´-chloro-1´,2´,4´-thiadiazoyl-5´-ylthiomethyl)-sulfoxide (2) have been separated by liquid chromatography on triacetylcellulose. Tested in a photometer assay on Torulopsis H 24 and Erwinia carotovorum (+)-2 and (-)...

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Published inZeitschrift für Naturforschung. B, A journal of chemical sciences Vol. 47; no. 4; pp. 597 - 599
Main Authors Walek, Wolfgang, Fieseler, Christine, Schneider, Peter, Fischer, Gerhard W.
Format Journal Article
LanguageEnglish
Published Verlag der Zeitschrift für Naturforschung 01.04.1992
Subjects
Bactericide
Enantiomeric Resolution
Fungicide
Liquid Chromatography
Thiadiazolyl Sulfoxide
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Summary:The enantiomers of the fungicidal and bactericidal (3-chloro-1,2,4-thiadiazol-5-yl)-(3´-chloro-1´,2´,4´-thiadiazoyl-5´-ylthiomethyl)-sulfoxide (2) have been separated by liquid chromatography on triacetylcellulose. Tested in a photometer assay on Torulopsis H 24 and Erwinia carotovorum (+)-2 and (-)-2 show practically the same activity and do not differ from the racemic mixture.
ISSN:0932-0776
1865-7117
DOI:10.1515/znb-1992-0424