Cover Picture: Proteolytic Actuation of Nanoparticle Self-Assembly (Angew. Chem. Int. Ed. 19/2006)
Sterically shielded …︁…︁ nanoparticles diffuse freely in solution and biological fluids until proteases expressed by cancer cells trigger them to self‐assemble. In their Communication on page 3161ff., S. N. Bhatia and co‐workers show that complimentary Fe3O4 nanoparticle binding is inhibited by the...
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Published in | Angewandte Chemie (International ed.) Vol. 45; no. 19; p. 2985 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Weinheim
WILEY-VCH Verlag
05.05.2006
WILEY‐VCH Verlag |
Subjects | |
Online Access | Get full text |
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Summary: | Sterically shielded …︁…︁ nanoparticles diffuse freely in solution and biological fluids until proteases expressed by cancer cells trigger them to self‐assemble. In their Communication on page 3161ff., S. N. Bhatia and co‐workers show that complimentary Fe3O4 nanoparticle binding is inhibited by the attachment of protease‐cleavable polymers. Cleavage of these polymers triggers “latent” nanoparticles to form multimeric assemblies with emergent properties. |
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Bibliography: | istex:8386EBF35BF3CD2C6397D1601CD17AD090C0A9FF ArticleID:ANIE200690067 ark:/67375/WNG-FKZMN8C7-Z These authors contributed equally |
ISSN: | 1433-7851 1521-3773 |
DOI: | 10.1002/anie.200690067 |