Role of biomarkers in the heart failure clinic

• Published in: Kosin Medical Journal (Online) Vol. 37; no. 1; pp. 4 - 17
• Main Authors: Kim, Bong-Joon, Park, Jae-Hyeong
• Format: Journal Article
• Language: English
• Published: Kosin University College of Medicine 01.03.2022; 고신대학교 의과대학 학술지
• Subjects: biomarker; galectin-3; natriuretic peptides; soluble st2; troponin; 의학일반
• ISSN: 2005-9531; 2586-7024
• DOI: 10.7180/kmj.22.019

Heart failure (HF) is a common cardiovascular disease that has a complex pathophysiology. Because it is the final stage of many cardiovascular diseases, proper diagnosis and treatment are crucial for prolonging patients’ survival and improving their well-being. Several biomarkers have been identified in HF, and their roles in diagnosis and prognostication have been widely investigated. Among them, natriuretic peptides are key for diagnosing HF, predicting its prognosis, and monitoring the effectiveness of HF treatment. Moreover, natriuretic peptides can also be used to treat HF. In addition to natriuretic peptides, several other biomarkers were included in the most recent HF management guidelines. Thus, we reviewed the role of the biomarkers included in these guidelines and discussed future perspectives.