The Chemical Degradation of Folic Acid
2,4,7-Trihydroxypteridine is readily accessible from folic acid and other naturally occurring pteridines by way of 2-amino-4-hydroxypteridine-6-carboxylic acid, 2-amino-4-hydroxypteridine, and isoxanthopterin (2-amino-4,7-dihydroxypteridine). After irradiation with ultraviolet light and brief acid h...
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Published in | The Journal of biological chemistry Vol. 241; no. 2; pp. 379 - 382 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
American Society for Biochemistry and Molecular Biology
25.01.1966
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Online Access | Get full text |
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Summary: | 2,4,7-Trihydroxypteridine is readily accessible from folic acid and other naturally occurring pteridines by way of 2-amino-4-hydroxypteridine-6-carboxylic
acid, 2-amino-4-hydroxypteridine, and isoxanthopterin (2-amino-4,7-dihydroxypteridine). After irradiation with ultraviolet
light and brief acid hydrolysis, 2,4,7-trihydroxypteridine gives rise to glyoxylic acid coming from carbon atoms 6 and 7 of
the pteridine ring. A detailed method is described suitable for use on a micro scale in the study of the biosynthetic origin
of these carbon atoms in pteridines. |
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ISSN: | 0021-9258 1083-351X |
DOI: | 10.1016/S0021-9258(18)96927-9 |