ACTIVATION OF HUMAN BLOOD MONONUCLEARS BY LIPOPOLYSACCHARIDE OF DIFFERENT COMPOSITION

Influence of lipopolysaccharide (LPS) composition upon activation of human blood mononuclears was investigated, by measuring levels of pro-inflammatory TNFα and IL-6 cytokines released by the cells. It is shown that LPS from Rhodobacter capsulatus PG, in contrast to E. coli LPS, did not activate the...

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Published inMedit͡s︡inskai͡a︡ immunologii͡a Vol. 12; no. 4-5; pp. 405 - 408
Main Authors Zubova, S. V., Voloshina, E. V., Kosjakova, N. I., Grachev, S. V., Prokhorenko, I. R
Format Journal Article
LanguageEnglish
Russian
Published St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 17.07.2014
Subjects
blood serum
cytokines
human blood mononuclear cells
lipopolysaccharides
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Summary:Influence of lipopolysaccharide (LPS) composition upon activation of human blood mononuclears was investigated, by measuring levels of pro-inflammatory TNFα and IL-6 cytokines released by the cells. It is shown that LPS from Rhodobacter capsulatus PG, in contrast to E. coli LPS, did not activate the target cells for synthesis of the cytokines.
ISSN:1563-0625
2313-741X
DOI:10.15789/1563-0625-2010-4-5-405-408