Conceptual Study of Brain Dedicated PET Improving Sensitivity

• Published in: Progress in Medical Physics Vol. 27; no. 4; pp. 236 - 240
• Main Authors: Shin, Han-Back, Choi, Yong, Huh, Yoonsuk, Jung, Jin Ho, Suh, Tae Suk
• Format: Journal Article
• Language: English
• Published: 한국의학물리학회 01.12.2016
• Subjects: 방사선과학
• ISSN: 1226-5829; 2508-4445; 2288-9620; 2508-4453
• DOI: 10.14316/pmp.2016.27.4.236

The purpose of this study is to propose a novel high sensitivity neuro-PET design. The improvement of sensitivity in neuro-PET is important because it can reduce scan time and/or radiation dose. In this study, we proposed a novel PET detector design that combined conical shape detector with cylindrical one to obtain high sensitivity. The sensitivity as a function of the oblique angle and the ratio of the conical to cylindrical portion was estimated to optimize the design of brain PET using Monte Carlo simulation tool, GATE. An axial sensitivity and misplacement rate by penetration of γ rays were also estimated to evaluate the performance of the proposed PET. The sensitivity was improved by 36% at the center of axial FOV. This value was similar to the calculated value. The misplacement rate of conical shaped PET was about 5% higher than the conventional PET. The results of this study demonstrated the conical detector proposed in this study could provide subsequent improvement in sensitivity which could allow to design high sensitivity PET for brain imaging. KCI Citation Count: 0