Bone Mineral Density in Thyroid Cancer Patients: Data from the Korea National Health and Nutrition Examination Survey

• Published in: Journal of endocrine surgery Vol. 17; no. 4; pp. 153 - 159
• Main Author: Chang, Myung-Chul
• Format: Journal Article
• Language: English
• Published: 대한갑상선-내분비외과학회 01.12.2017
• Subjects: 일반외과학
• ISSN: 2508-8149; 2508-8459
• DOI: 10.16956/jes.2017.17.4.153

Purpose: There are conflicting results about bone mineral density (BMD) after thyroidstimulating hormone (TSH) suppression in thyroid cancer treatment. This study used the Korea National Health and Nutrition Examination Survey (KNHANES) data to investigate BMD of thyroid cancer patients in Korea. Methods: The data were collected from 2008 to 2011 of the KNHANES IV–V. Among a total of 37,753 participants, 18,618 subjects were included. Osteopenia and osteoporosis were evaluated according the past history of thyroid cancer. Subgroups of women and postmenopausal women were analyzed using the same method. Results: Among the 18,618 subjects, 80 thyroid cancer cases were observed. There was no significant difference in osteopenia and osteoporosis with or without thyroid cancer history (P=0.783). In the subgroup analyses of women, no difference was observed in BMD according thyroid cancer history (P=0.685). In the post-menopausal women, osteopenia and osteoporosis were less frequent in thyroid cancer cases in univariate analysis (P=0.003), but that was not significant in multivariate analysis (P=0.095). Conclusion: Although the KNHANES had a small number of thyroid cancer cases, no data about TSH suppression, and short follow-up periods, no significant difference in BMD with or without thyroid cancer was observed. The subgroup analyses of women and postmenopausal women showed similar results. KCI Citation Count: 0