MAJOR INTERCELLULAR INTERACTIONS AT THE T CELL ACTIVATION IN RENAL TRANSPLANT REJECTION

Currently, an organ rejection is a leading cause of kidney transplants loss. Effective therapy is impossible without a clear understanding of the rejection mechanisms. In this paper, we summarize the views of domestic and foreign authors on the role of T cell activation in kidney transplant rejectio...

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Published inAlʹmanakh klinicheskoĭ medit͡s︡iny Vol. 1; no. 31; pp. 76 - 82
Main Authors Vatazin, A. V., Zul’karnaev, A. B., Fedulkina, V. A., Krstic, M.
Format Journal Article
LanguageEnglish
Russian
Published MONIKI 13.02.2016
Subjects
antigen-presenting cells
cell activation
co-stimulation
immune response
т cells
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Summary:Currently, an organ rejection is a leading cause of kidney transplants loss. Effective therapy is impossible without a clear understanding of the rejection mechanisms. In this paper, we summarize the views of domestic and foreign authors on the role of T cell activation in kidney transplant rejection.
ISSN:2072-0505
2587-9294
DOI:10.18786/2072-0505-2014-31-76-82