Features of acute megakaryoblastic leukemia diagnosis in a child with Down syndrome
We present a description of the difficulties in diagnosing acute megakaryoblastic leukemia in a child with Down syndrome aggravated by multiple comorbidities. In this case, a comprehensive assessment of clinical data, the results of an automatic complete blood count with a detailed interpretation of...
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Published in | Onkogematologii͡a Vol. 18; no. 1; pp. 31 - 38 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English Russian |
Published |
ABV-press
14.03.2023
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Abstract | We present a description of the difficulties in diagnosing acute megakaryoblastic leukemia in a child with Down syndrome aggravated by multiple comorbidities. In this case, a comprehensive assessment of clinical data, the results of an automatic complete blood count with a detailed interpretation of the entire range of parameters, as well as morphological and immunophenotypic bone marrow examination using an extended panel of monoclonal antibodies played a key role in the diagnosis. |
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AbstractList | We present a description of the difficulties in diagnosing acute megakaryoblastic leukemia in a child with Down syndrome aggravated by multiple comorbidities. In this case, a comprehensive assessment of clinical data, the results of an automatic complete blood count with a detailed interpretation of the entire range of parameters, as well as morphological and immunophenotypic bone marrow examination using an extended panel of monoclonal antibodies played a key role in the diagnosis. |
Author | Guskova, N. K. Lysenko, I. B. Baranenkova, M. A. Kozyuk, O. V. Kozel, Yu. Yu Dmitrieva, V. V. Nozdricheva, A. S. Selyutina, O. N. |
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SubjectTerms | acute megakaryoblastic leukemia acute myeloid leukemia down syndrome flow cytometry morphological examination of the bone marrow |
Title | Features of acute megakaryoblastic leukemia diagnosis in a child with Down syndrome |
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