The spectrum of pollen sensitization in children with allergic diseases living in the Rostov region

• Published in: Medicinskij vestnik Ûga Rossii Vol. 14; no. 1; pp. 50 - 55
• Main Authors: Lebedenko, A. A., Semernik, O. E., Yanchenko, V. V., Alyakhnovich, N. S., Rudyakova, V. S.
• Format: Journal Article
• Language: English
• Published: State Budget Educational Institute of Higher Professional Education, Rostov State Medical University, Ministry Health of Russian Federation 28.03.2023
• Subjects: allergen; atopic dermatitis; bronchial asthma; pollen; sensitization
• ISSN: 2219-8075; 2618-7876
• DOI: 10.21886/2219-8075-2023-14-1-50-55

Objective : to investigate the characteristics of pollen sensitization in children with established diagnoses of bronchial asthma (BA) and atopic dermatitis (AD) living in the Rostov region. Materials and methods : patients suffering from BA (n = 53), they made up the first group and patients with AD (n = 65), the second group were examined. All children underwent a comprehensive clinical and laboratory examination. Immunochemiluminescent assay by the Immulight 2000XPi analyzer was used to determine specific IgE. Results : the analysis of the obtained results showed that sensitization to tree pollen was quite often noted - at least a quarter of those examined with BA and about 20% of children with AD had elevated titers of specific IgE to these allergens. The study of the level of specific IgE to meadow grass pollen showed that in the first group an allergic reaction to pollen of bent grass (31.5%), bonfire (33.3%), timothy grass (29.6%) and fescue (28.3%) was noted more often. In the second group, elevated levels of specific IgE were registered in relation to grasses such as bent grass (31.80%), bonfire (27.7%) and timothy grass (21.5%). The highest level of sensitization in patients with respiratory manifestations of allergy was registered in relation to weed pollen: ragweed (40.7%), quinoa (22.2%) and chamomile (14.8%). Conclusion : this study made it possible to identify allergens that play the most important role in the pathogenesis of BA and AD in children living in the Rostov region.