Effect of Surgery for Fungal Sinusitis on the Clinical Course of Rheumatoid Arthritis

In a previous study conducted at our department, we found many cases of fungal sinusitis during screening CT performed during immunosuppressive treatment for patients with rheumatoid arthritis. In recent years, chronic sinusitis has been reported as a risk factor for rheumatoid arthritis in many cas...

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Published inNippon Jibiinkoka Tokeibugeka Gakkai Kaiho(Tokyo) Vol. 127; no. 7; pp. 774 - 779
Main Authors Kaminota, Teppei, Aritomo, Hiroshi, Ohara, Yudai, Kanou, Takuya, Tanaka, Takemichi, Shinomori, Yusuke
Format Journal Article
LanguageJapanese
English
Published Japanese Society of Otorhinolaryngology-Head and Neck Surgery 20.07.2024
Subjects
disease activity index
endoscopic sinus surgery
fungal sinusitis
rheumatoid arthritis
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Summary:In a previous study conducted at our department, we found many cases of fungal sinusitis during screening CT performed during immunosuppressive treatment for patients with rheumatoid arthritis. In recent years, chronic sinusitis has been reported as a risk factor for rheumatoid arthritis in many cases, but there are few reports on how treatment for one might affect the clinical course of the other in patients with chronic sinusitis and rheumatoid arthritis. In this study, we examined the effect of surgery for fungal sinusitis on the clinical course of rheumatoid arthritis. Of the 22 cases of fungal sinusitis with rheumatoid arthritis that underwent endoscopic sinus surgery at our department between January 2017 and December 2021, we enrolled 14 cases in which the course of rheumatoid arthritis could be followed for at least one year before and after the surgery in this study. The values of DAS (Disease Activity Score) 28-CRP, CDAI (Clinical Disease Activity Index), and SDAI (Simplified Disease Activity Index), which are disease activity indices for rheumatoid arthritis, measured prior to the surgery were compared with those measured at 3, 6, and 12 months after the surgery. The values of all the indices were significantly lower at each of the time-points after surgery as compared with the values measured preoperatively, suggesting that surgery for fungal sinusitis may improve the clinical course of rheumatoid arthritis.
ISSN:2436-5793
2436-5866
DOI:10.3950/jibiinkotokeibu.127.7_774