Control of cell-type generation mediated by growth factor

A working hypothesis is presented, suggesting that the binary control of cell-type generation by external signals operates in an indirect way: growth factor as the signal affects the mode of cell-cycle progression of precursor cells. The mode of cell-cycle progression that is realised decides the pa...

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Bibliographic Details
Published inTrends in Genetics Vol. 2; pp. 267 - 268
Main Author Yamada, Tuneo
Format Book Review Journal Article
LanguageEnglish
Published Elsevier Ltd 1986
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Summary:A working hypothesis is presented, suggesting that the binary control of cell-type generation by external signals operates in an indirect way: growth factor as the signal affects the mode of cell-cycle progression of precursor cells. The mode of cell-cycle progression that is realised decides the pathway of cell-type generation.
ISSN:0168-9525
DOI:10.1016/0168-9525(86)90261-1