Modification of sensitization methods can induce allergic inflammation in the lungs of allergy-resistant Sprague Dawley rats

In multi-point sensitized SD rats (n=8), OA exposure induced pulmonary function changes that included a significant increase in lung resistance (RL) (p<0.001) and decrease in dynamic lung compliance (Cydn) (p<0.001), compared with sham-sensitized rats.

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Bibliographic Details
Published inJournal of allergy and clinical immunology Vol. 115; no. 2; p. S48
Main Authors Wong, Y.O., Sung, R.Y.T., Yang, Q.H., Chan, W.Y., Li, K., Zhao, Y., Li, A.M., Fok, T.F., Fung, K.P.
Format Journal Article
LanguageEnglish
Published St. Louis Mosby, Inc 01.02.2005
Elsevier Limited
Subjects
Allergies
Lungs
Methods
Rodents
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Summary:In multi-point sensitized SD rats (n=8), OA exposure induced pulmonary function changes that included a significant increase in lung resistance (RL) (p<0.001) and decrease in dynamic lung compliance (Cydn) (p<0.001), compared with sham-sensitized rats.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2004.12.208