Unit Of Allergy In An Oncology Institute. First Nationale Experience In Spain . About The First 800 Desensitizations To Chemotherapeutics And Monoclonal Antibodies

FIRST NATIONALE EXPERIENCE in SPAIN. Methods 2 Part-time allergists, 1 nurse specialized in drug allergy, 1 Pharmaceutical, under the coordination of 1 Head of Unit First visit, skin tests, risk stratification and desensitization decision, place and number of steps The desensitization protocols used...

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Bibliographic Details
Published inJournal of allergy and clinical immunology Vol. 141; no. 2; p. AB44
Main Author Martí-Guadano, Enrique A.
Format Journal Article
LanguageEnglish
Published St. Louis Elsevier Inc 01.02.2018
Elsevier Limited
Subjects
Allergies
Chemotherapy
Desensitization
Monoclonal antibodies
United States > US
Spain
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Summary:FIRST NATIONALE EXPERIENCE in SPAIN. Methods 2 Part-time allergists, 1 nurse specialized in drug allergy, 1 Pharmaceutical, under the coordination of 1 Head of Unit First visit, skin tests, risk stratification and desensitization decision, place and number of steps The desensitization protocols used are from Brigham and Women's Hospital of Boston Results 285 patients, with different types and stages of cancer; 801 cycles of desensitization, mainly to Platins and taxanes; 98% of successes (reaching final dose prescribed by oncologist) 70% were 12-step cycles and 25% of 16; All in Day Hospital Conclusions A Chemotherapy Drug Desensitization Unit, managed by allergists, increases the population's survival expectations with cancer, being able to maintain the first therapeutic line, recommended by the international guidelines, and that of another Form, they are confronted with second choices, safer perhaps, but clearly less effective
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2017.12.143