Serum Albumin

Being one of the most abundant proteins in human and other mammals, albumin plays a crucial role in transporting various endogenous and exogenous molecules and maintaining of colloid osmotic pressure of the blood. It is not only the passive but also the active participant of the pharmacokinetic and...

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Published inEncyclopedia (Basel, Switzerland) Vol. 1; no. 1; pp. 65 - 75
Main Authors Belinskaia, Daria A., Voronina, Polina A., Batalova, Anastasia A., Goncharov, Nikolay V.
Format Journal Article
LanguageEnglish
Published Naples MDPI AG 01.01.2021
Subjects
Amino acids
Binding sites
Enzymes
Ligands
Molecular weight
Polypeptides
Proteins
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Summary:Being one of the most abundant proteins in human and other mammals, albumin plays a crucial role in transporting various endogenous and exogenous molecules and maintaining of colloid osmotic pressure of the blood. It is not only the passive but also the active participant of the pharmacokinetic and toxicokinetic processes possessing a number of enzymatic activities. A free thiol group of the albumin molecule determines the participation of the protein in redox reactions. Its activity is not limited to interaction with other molecules entering the blood: of great physiological importance is its interaction with the cells of blood, blood vessels and also outside the vascular bed. This entry contains data on the enzymatic, inflammatory and antioxidant properties of serum albumin.
ISSN:2673-8392
2673-8392
DOI:10.3390/encyclopedia1010009