Role of TRIM16 in cancers development
Тhe protein TRIM16 is involved in key intracellular processes, such as proliferation, cell differentiation and programmed death, including intrinsic and extrinsic apoptosis, autophagy-dependent cell death and immunogenic cell death. The TRIM16 protein acts the proteins TPD43, Gli-1, RARβ, Snail comp...
Saved in:
Published in | Uspehi molekulârnoj onkologii Vol. 5; no. 4; pp. 72 - 77 |
---|---|
Main Authors | , , |
Format | Journal Article |
Language | English Russian |
Published |
ABV-press
04.01.2019
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | Тhe protein TRIM16 is involved in key intracellular processes, such as proliferation, cell differentiation and programmed death, including intrinsic and extrinsic apoptosis, autophagy-dependent cell death and immunogenic cell death. The TRIM16 protein acts the proteins TPD43, Gli-1, RARβ, Snail components and MAPK signaling pathway, cadherins, caspases and is also associated with the regulation of the immune system via direct and indirect mechanisms. The influence of TRIM16 protein on the pathogenesis of hormone-dependent tumors is well-known. Further study of the TRIM16 role in the development and progression of malignant neoplasms will form the basis for the development of new methods for predicting the course of the malignant process. |
---|---|
ISSN: | 2313-805X 2413-3787 |
DOI: | 10.17650/2313-805X-2018-5-4-72-77 |