In Silico Studies and Histopathological Analysis on the Bioremediation Effect of Spirulina in Various Tissues of Diclofenac Treated Pangasius Sps

The aquatic biome is an integral part of Earth's survival. Humans, with an attitude to lead a comfortable life, have invaded the ecosystem to a larger extent owing to many direct and indirect catastrophes in the longer run. Our aim was to establish the link between the genes and compounds that...

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Bibliographic Details
Published inToxicology international pp. 239 - 244
Main Authors Shreenidhi, K. S., Sri Santhanam, Saranya, Bhaskar, Shreaya, Narayan Sridhar, Sowmia, Vijaya Geetha, B.
Format Journal Article
LanguageEnglish
Published 23.08.2021
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Summary:The aquatic biome is an integral part of Earth's survival. Humans, with an attitude to lead a comfortable life, have invaded the ecosystem to a larger extent owing to many direct and indirect catastrophes in the longer run. Our aim was to establish the link between the genes and compounds that turn toxic to the organisms over due course of time. With the selected compound as diclofenac, Comparative Toxicogenomics database was used to identify the diseases related to the compounds, the top expressing genes, and the common genes of the compounds. By incorporating the coalescence of spirulina bioremediation under histopathological studies, the effect of the algae was observed. From these two studies, we were able to conclude that there was a significant link between the effects of the compound on the organisms.
ISSN:0971-6580
0976-5131
DOI:10.18311/ti/2021/v28i3/27327