Celiac disease: uncommon, oligosymptomatic course of illness, with profound hypoalbuminemia in an adult patient

Celiac disease (CD) is an immune-mediated disease, caused by gluten, occurring in people with genetic predisposition. The course of the disease can vary and includes both intestinal and extra-intestinal manifestations. Many patients are undiagnosed for many years and some of them, in particular with...

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Published inArchive of clinical cases Vol. 6; no. 2; pp. 31 - 36
Main Authors Lis, Lukasz, Konieczny, Andrzej, Jerzak, Patryk, Podgorski, Pawel, Benc, Krzysztof, Hruby, Zbigniew
Format Journal Article
LanguageEnglish
Published Iași, Romania Archive of Clinical Cases 01.06.2019
UMF “Gr. T. Popa” Iasi Publishing House
Subjects
Autoimmune diseases
Case Report
Celiac disease
Development and progression
Fractures (Injuries)
Gluten
Malnutrition
Osteoporosis
Proteinuria
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Summary:Celiac disease (CD) is an immune-mediated disease, caused by gluten, occurring in people with genetic predisposition. The course of the disease can vary and includes both intestinal and extra-intestinal manifestations. Many patients are undiagnosed for many years and some of them, in particular with nonspecific symptoms or asymptomatic, might never be diagnosed. We present a rare case of a patient, who's first and practically the only symptom of the disease was a pathological fracture of the ribs. In addition, despite the lack of clinical symptoms of malabsorption syndrome, malnutrition and proteinuria, we observed profound hypoalbuminemia and hypoproteinemia. This case suggests that CD diagnostic should be undertaken in evaluation of every patient with osteoporotic fractures and hypoalbuminemia. Keywords: celiac disease; hypoalbuminemia; autoimmune diseases
ISSN:2360-6975
2360-6975
DOI:10.22551/2019.23.0602.10151