Autosomal Short Tandem Repeat (STR) Variation Based on 15 Loci in a Population from the Central Region (Riyadh Province) of Saudi Arabia

• Published in: Journal of forensics research Vol. 6; no. 1; p. 1
• Main Authors: Osman, Awad E, Alsafar, Habiba
• Format: Journal Article
• Language: English
• Published: 2015
• ISSN: 2157-7145; 2157-7145
• DOI: 10.4172/2157-7145.1000267

The small size of Short Tandem Repeats (STR), their ubiquitous genome-wide distribution and polymorphic nature enhances their value in human forensic/population genetics applications. This study aims to investigate the short tandem repeat variation based on 15 loci in a population from the central region of Saudi Arabia. Allele frequency variation for 15 STR loci was examined in 190 unrelated Saudi volunteers. This study summarizes the allele distribution in the Saudi population and compares them to other populations located in Asia, Africa, the Middle East and Europe. The standard forensic parameters of Observed Hetrozygosity (Ho), Expected Heterozygosity (He) and Gene Diversity Index (GD) were determined for the following 15 STR loci: D8S1179, D21S1, D7S820, CSF1PO, D3S1358, TH0, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S5, D5S818 and FGA. The most frequent alleles in the Saudi population were: 8 repeats (0.558) at TPOX, 12 (0.411) at D13S317, 12 (0.385) at CSF1PO, 11 (0.382) at D16D539 and 10 (0.358) at D7S820.