Efficacy of Herbal Medicine as an Adjunctive Therapy of Chemotherapy for Cervical Cancer: A Systematic Review and Meta-analysis

This study aimed to evaluate the efficacy of herbal medicine (HM) combined with chemotherapy (CT) for cervical cancer. Ten electronic databases including Pubmed, Cochrane library, Embase, Korean databases, and Chinese medical databases were systematically searched up to October 2019. All randomized...

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Bibliographic Details
Published inJournal of Physiology & Pathology in Korean Medicine Vol. 34; no. 5; pp. 255 - 262
Main Authors Oh, Seung Yun, Kim, Mi Suk, Joo, Jong Cheon, Song, Yung Sun
Format Journal Article
LanguageEnglish
Published 한의병리학회 25.10.2020
Subjects
한의학
Herbal medicine
Systematic review
Chemotherapy
Cervical cancer
Meta-analysis
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ISSN1738-7698
2288-2529
DOI10.15188/kjopp.2020.10.34.5.255

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Summary:This study aimed to evaluate the efficacy of herbal medicine (HM) combined with chemotherapy (CT) for cervical cancer. Ten electronic databases including Pubmed, Cochrane library, Embase, Korean databases, and Chinese medical databases were systematically searched up to October 2019. All randomized controlled trials with HM combined with CT to treat cervical cancer were included. A total of 21 trials were included for analysis. Compared to the control group, HM combined with CT group significantly increased tumor response (complete and partial response) (risk ratio [RR] = 1.24, 95% CI: 1.15–1.33, p < 0.00001) and Karnofsky performance score (standardized mean difference [SMD] = 1.71, 95% CI: 1.41–2.01, p < 0.00001). Also, HM combined with CT group remarkably reduced CT toxicity. In Conclusion, our study suggests that HM might be a potential option for cervical cancer to enhance curative efficacy and reduce CT toxicity. KCI Citation Count: 0
Bibliography:https://kmpath.jams.or.kr
ISSN:1738-7698
2288-2529
DOI:10.15188/kjopp.2020.10.34.5.255