GUANIDINE-ANNELATED HETEROCYCLES XVI. A PRACTICAL SYNTHESIS OF 7-CHLORO-4-PHENYLAMINO[1,2,4]TRIAZOLOQUINAZOLIN-5(4H)-ONES

The triazolo[2,3-a]quinazolin-5(4H-ones 9a-c can be prepared via Dimroth rearrangement by treatment of 5 with representative carboxylic acid orthoesters 6a-c each heating at 40 degrees C more elevated temperature than the preparation of their analogous triazolo[4,3-a] isomers 7a-c.

Saved in:
Bibliographic Details
Published inHeterocycles Vol. 75; no. 10; pp. 2421 - 2428
Main Authors Hsu, Wen-Chuan, Shan, Pei-Wen, Huang, Yi-Chen, Liu, Kang-Chien, Chang, Tsu-Chung
Format Journal Article
LanguageEnglish
Published OXFORD Elsevier 01.10.2008
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
Dimroth Rearrangement
1,2,4-TRIAZOLES
Catalyzed by Heat
CONDENSED 1,3-BENZOTHIAZINONES
ESTROGEN-RECEPTOR
Isomer
Online AccessGet more information

Cover

More Information
Summary:The triazolo[2,3-a]quinazolin-5(4H-ones 9a-c can be prepared via Dimroth rearrangement by treatment of 5 with representative carboxylic acid orthoesters 6a-c each heating at 40 degrees C more elevated temperature than the preparation of their analogous triazolo[4,3-a] isomers 7a-c.
ISSN:0385-5414
1881-0942
DOI:10.3987/COM-08-11406