The etiology of viral respiratory infections in infants with community-acquired pneumonia
Background: Community-acquired pneumonia can be caused by both bacterial and viral pathogens. The differential diagnosis based only on clinical data is not always feasible. The use of C-reactive protein (CRP) and procalcitonin might give some additional information for treatment decision-making.Aim:...
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Published in | Alʹmanakh klinicheskoĭ medit͡s︡iny Vol. 45; no. 1; pp. 2 - 7 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English Russian |
Published |
MONIKI
01.02.2017
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Subjects | |
Online Access | Get full text |
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Summary: | Background: Community-acquired pneumonia can be caused by both bacterial and viral pathogens. The differential diagnosis based only on clinical data is not always feasible. The use of C-reactive protein (CRP) and procalcitonin might give some additional information for treatment decision-making.Aim: To evaluate the structure and rates of viral isolation in community-acquired pneumonia in hospitalized infants and changes in CRP and procalcitonin levels.Materials and methods: Seventy five infants at the age of up to 11 months and 29 days, who were hospitalized with community-acquired pneumonia confirmed by chest X-ray from March 2015 till February 2016, were included into the study. CRP and procalcitonin levels were measured. Detection of viruses in nasopharyngeal swabs was performed by a real-time polymerase chain reaction.Results: Nucleic acids of respiratory viruses were isolated in 72% (54/75) of infants. The most common were respiratory syncytial virus (in 70.4%, 38/54) and human rhinovirus (in 16.6%, 9/54). Median of white blood cell count in pneumonia associated with respiratory viruses was 10.95 (9; 14.1)×109/L, CRP level, 1.95 (0.5; 7) mg/L, procalcitonin level, 0.087 (0.067; 0.17) ng/mL.Conclusion: The study showed a high prevalence of respiratory viruses in community-acquired pneumonia in infants. There was no increase in CRP and procalcitonin levels in pneumonia associated with respiratory viruses. |
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ISSN: | 2072-0505 2587-9294 |
DOI: | 10.18786/2072-0505-2017-45-1-2-7 |