POLYMORPHISM OF CHRONIC GLOMERULONEPHRITIS ASSOCIATION WITH ADPRT1 GENE VAL762ALA

Association of polymorphic ADPRT1 gene Val762Ala marker, encoding poly(ADP-ribose)polymerase-l, with the development, course and progress of chronic glomerulonephritis was revealed during investigation. The risk of the chronic glomerulonephritis development is higher in patients-carriers of Val-alle...

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Published inAlʹmanakh klinicheskoĭ medit͡s︡iny no. 30; pp. 32 - 36
Main Authors Kamyshova, E. S., Shvetsov, M. Yu, Shestakov, A. E., Kutyrina, I. M., Nosikov, V. V.
Format Journal Article
LanguageEnglish
Russian
Published MONIKI 01.03.2016
Subjects
adprt1
chronic glomerulonephritis
genetic susceptibility
val762ala polymorphism
ген adprt1
генетическая предрасположенность
полиморфный маркер val762ala
хронический гломерулонефрит
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Summary:Association of polymorphic ADPRT1 gene Val762Ala marker, encoding poly(ADP-ribose)polymerase-l, with the development, course and progress of chronic glomerulonephritis was revealed during investigation. The risk of the chronic glomerulonephritis development is higher in patients-carriers of Val-allele and Val/Val-genotype and lower in those with Ala-allele and Ala/Ala-genotype.
ISSN:2072-0505
2587-9294
DOI:10.18786/2072-0505-2014-30-32-36