Cognitive impairment in patients with coronavirus infection

The pathogenesis of the development of cognitive impairment (CI) associated with the SARS-CoV-2 virus is complex and includes the direct neurotoxic effect of the virus, vascular, disimmune factors, artificial lung ventilation, and adverse psychological consequences of social isolation. The relations...

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Bibliographic Details
Published inNevrologii͡a︡, neĭropsikhiatrii͡a︡, psikhosomatika Vol. 14; no. 4; pp. 96 - 102
Main Authors Starchina, Y. A., Kosivtsova, O. V.
Format Journal Article
LanguageEnglish
Russian
Published IMA-PRESS LLC 24.08.2022
Subjects
alzheimer's disease
cognitive impairment
coronavirus
covid-19
dementia
memantine
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Summary:The pathogenesis of the development of cognitive impairment (CI) associated with the SARS-CoV-2 virus is complex and includes the direct neurotoxic effect of the virus, vascular, disimmune factors, artificial lung ventilation, and adverse psychological consequences of social isolation. The relationship between CI and SARS-CoV-2 infection appears to be two-way: patients with premorbid CI have a higher risk of infection, severe illness, and death; on the other hand, past infection with SARS-CoV-2 may stimulate the clinical onset and progression of CI, including Alzheimer's disease. For the treatment of severe CI after COVID-19, memantine (akatinol memantine) is recommended.
ISSN:2074-2711
2310-1342
DOI:10.14412/2074-2711-2022-4-96-102