A compact population analysis test using 32 SNPs with highly diverse allele frequency distributions

A total of 32 population informative SNP markers have been combined into a single multiplex PCR test. Studies of samples from three major population groups indicate strongly contrasting allele frequency distributions in all the loci. A statistical analysis of SNP profiles using measurement of maximu...

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Bibliographic Details
Published inInternational Congress series Vol. 1288; pp. 58 - 60
Main Authors Phillips, C., Sanchez, J., Fontadevila, M., Gómez-Tato, A., Alvarez-Dios, J., Calaza, M., Casares de Cal, M., Ballard, D., Salas, A., Carracedo, A.
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.04.2006
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Summary:A total of 32 population informative SNP markers have been combined into a single multiplex PCR test. Studies of samples from three major population groups indicate strongly contrasting allele frequency distributions in all the loci. A statistical analysis of SNP profiles using measurement of maximum likelihood provides a system for predicting population of origin with a very low error rate. This analysis system will form a core part of an open access web portal.
ISSN:0531-5131
1873-6157
DOI:10.1016/j.ics.2005.10.023