Probable recurrence of cardiac sarcoidosis in a transplanted heart

Recurrence of cardiac sarcoidosis (CS) in post-transplant patients presents a rare but potentially life-threatening form of graft dysfunction and poses challenges due to varying clinical presentations, limited diagnostic modalities, and treatments based on anecdotal evidence. We discuss the case of...

Full description

Saved in:
Bibliographic Details
Published inJHLT Open Vol. 6; p. 100146
Main Authors Seplowe, Matthew, Khan, Shazli, Vemulakonda, Lakshmisree, Shakil, Fouzia, Michaud, Liana, Aggarwal-Gupta, Chhaya, Lanier, Gregg, Levine, Avi, Ohira, Suguru, Spielvogel, David, Gass, Alan, Pan, Stephen
Format Journal Article
LanguageEnglish
Published Elsevier Inc 01.11.2024
Elsevier
Subjects
cardiac sarcoidosis
graft dysfunction
immunosuppression
orthotopic heart transplant
recurrent sarcoidosis
graft dysfunction
immunosuppression
cardiac sarcoidosis
recurrent sarcoidosis
orthotopic heart transplant
Online AccessGet full text

Cover

More Information
Summary:Recurrence of cardiac sarcoidosis (CS) in post-transplant patients presents a rare but potentially life-threatening form of graft dysfunction and poses challenges due to varying clinical presentations, limited diagnostic modalities, and treatments based on anecdotal evidence. We discuss the case of a 46-year-old woman with CS, who developed cardiogenic shock necessitating orthotopic heart transplant. She subsequently developed likely recurrent CS in the transplanted heart. We discuss the rarity of this scenario as well as diagnostic modalities and management principles to consider.
ISSN:2950-1334
2950-1334
DOI:10.1016/j.jhlto.2024.100146