Fabrication of cerium oxide and β-Ni(OH)2 nano hexagonal architectures assembled on reduced graphene oxide for non-enzymatic electrochemical detection of glucose

• Published in: Ionics Vol. 28; no. 4; pp. 1957 - 1972
• Main Authors: S.G, Manjushree, Adarakatti, Prashanth S., Udayakumar, Velu, Almalki, Abdulraheem S. A.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 2022; Springer Nature B.V
• Subjects: Beverages; Cerium oxides; Chemistry; Chemistry and Materials Science; Condensed Matter Physics; Electrochemical analysis; Electrochemistry; Energy Storage; Glucose; Graphene; Nanoparticles; Nickel compounds; Optical and Electronic Materials; Original Paper; Oxidation; Renewable and Green Energy; Reproducibility; Selectivity; Sensors; Synergistic effect; X ray photoelectron spectroscopy; Cyclic voltammetry and amperometry; Nickel hydroxide; Reduced graphene oxide; Electrochemical sensor; Cerium oxide; Blood serum
• ISSN: 0947-7047; 1862-0760
• DOI: 10.1007/s11581-022-04451-4

The β-Ni(OH) 2 wrapped with cerium oxide on reduced graphene oxide (rGO) composite (CeNi@rGO) with hexagonal architectures were prepared over a simplistic precipitation followed by hydrothermal method, which were made up of nanosheets of β-Ni(OH) 2 with Ce 2 O 3 nanoparticles produced in situ on their surface. The composite was characterized by various techniques such as FT-IR, HRTEM-SAED, SEM–EDS, XRD, BET surface area analysis, XPS, and electrochemical technology. The results revealed that the components like cerium oxide, reduced graphene oxide, and nickel hydroxide of CeNi@rGO had a synergistic effect on improving electrochemical performance toward glucose. With a lower detection limit of 13 µM (S/N = 3), the glucose concentration was linearly proportional to the oxidation current from 50 to 1000 µM, with a high sensitivity of 33.1 μA μM −1  cm −2 . Furthermore, the sensor showed excellent reproducibility, repeatability, selectivity, and stability. We also demonstrated the usefulness of the created sensor in determining glucose in serum of human blood and sweetened beverages, with recoveries that were comparable to those obtained with a commercial glucose sensor. These findings suggest that the current research point to the possibility of enzyme-free glucose sensors of new generation for biochemical and clinical applications.